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The fallacy of reduction
Author(s) -
Rewers Marian
Publication year - 2012
Publication title -
pediatric diabetes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.678
H-Index - 75
eISSN - 1399-5448
pISSN - 1399-543X
DOI - 10.1111/j.1399-5448.2011.00832.x
Subject(s) - medicine , autoimmunity , fallacy , diabetes mellitus , insulin resistance , islet , etiology , type 1 diabetes , type 2 diabetes , pandemic , covid-19 , immunology , intensive care medicine , endocrinology , disease , infectious disease (medical specialty) , philosophy , epistemology
The “accelerator hypothesis” has made a significant impact on research into the etiology of type 1 diabetes. Some, but not all prospective studies have confirmed a weak association between insulin resistance and faster progression to diabetes among persons with advanced islet autoimmunity. However, there is hardly any evidence that insulin resistance can cause development of islet autoimmunity, thus be responsible for the ongoing pandemic of type 1 diabetes in children.