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Acute juvenile cataract in newly diagnosed type 1 diabetic patients: a description of six cases
Author(s) -
Iafusco Dario,
Prisco Francesco,
Romano Mario R.,
Dell'Omo Roberto,
Libondi Teodosio,
Costagliola Ciro
Publication year - 2011
Publication title -
pediatric diabetes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.678
H-Index - 75
eISSN - 1399-5448
pISSN - 1399-543X
DOI - 10.1111/j.1399-5448.2010.00749.x
Subject(s) - medicine , glycated hemoglobin , diabetes mellitus , diabetic ketoacidosis , glycemic , type 1 diabetes , type 2 diabetes , ketoacidosis , ophthalmology , gastroenterology , surgery , endocrinology
Iafusco D, Prisco F, Romano MR, Dell'Omo R, Libondi T, Costagliola C. Acute juvenile cataract in newly diagnosed type 1 diabetic patients: a description of six cases. Cataract represents one of the most frequent eye complications in type 1 and type 2 patients; contrarily, acute cataract in young diabetic patients occurs very rarely. The aim of this study was to describe six cases of acute cataract in adolescents at the onset of type 1 diabetes. Eight hundred and twenty‐six patients with type 1 diabetes were retrospectively studied. A multivariate analysis was applied to verify the weight of the following laboratory findings taken on admission (independent variables): glycemia, glycated hemoglobin (HbA1c), pH, base excess (BE),and on the occurrence of cataract (dependent variable). Six patients (0.7%) presented with acute lens opacities. Cataract development was significantly correlated with HbA1c and glycemia. The relative risk increases about twice for each percentage point from 12.8 to 14.1% of HbA1c; glycemic blood levels represent a moderate risk factor for cataractogenesis. Ketoacidosis and BE were not significantly correlated.