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Validation of capillary glycemia as a strategy for the screening of diabetes mellitus in adolescents
Author(s) -
Alvarez Marlene Merino,
Vieira Ana Carolina Reiff e,
Luiz Ronir Raggio,
Veiga Glória Valéria da
Publication year - 2009
Publication title -
pediatric diabetes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.678
H-Index - 75
eISSN - 1399-5448
pISSN - 1399-543X
DOI - 10.1111/j.1399-5448.2009.00508.x
Subject(s) - medicine , diabetes mellitus , endocrinology
Objective: To compare the degree of concordance between plasma and capillary glucose for screening of diabetes mellitus in adolescents. Methods: The plasma and capillary glucose of 119 adolescents aged 10–19 yr (36 males and 83 females) from public schools in Niterói, Rio de Janeiro State, Brazil, were verified after a 12‐h fast. Agreement was assessed through kappa statistics (k), McNemar’s chi‐squared test, and the intraclass correlation coefficient (ICC). The paired Student’s t ‐test for comparison of means, the approaches by Altman and Bland, and the survival–agreement plot were also applied. Results: Mean values of plasma glucose were 7.9 points higher than the capillary values (91.5 vs. 83.6 mg/dL, p < 0.001; ICC = 0.419). A regular agreement between the methods (k = 0.31, p < 0.001) for assessing proportions of adolescents with glycemia ≥100 mg/dL is observed. Using the strategy of adding 8 mg/dL to the capillary levels, the agreement improved (k = 0.46, p < 0.001) and a significant difference was not observed between the estimated prevalences (p = 0.815). Conclusions: The results suggest a satisfactory agreement between the two methods when capillary glucose is corrected, and this may be a useful and low‐cost tool for the epidemiologic investigation of diabetes mellitus prevalence in adolescents.