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Pediatric stroke associated with new onset type 1 diabetes mellitus: case reports and review of the literature
Author(s) -
Ho Josephine,
Mah Jean K.,
Hill Michael D.,
Pacaud Danièle
Publication year - 2006
Publication title -
pediatric diabetes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.678
H-Index - 75
eISSN - 1399-5448
pISSN - 1399-543X
DOI - 10.1111/j.1399-543x.2006.00151.x
Subject(s) - medicine , stroke (engine) , pediatrics , diabetes mellitus , type 1 diabetes , medline , type 2 diabetes mellitus , endocrinology , mechanical engineering , engineering , political science , law
Neurological deterioration in children with diabetic ketoacidosis (DKA) is commonly caused by cerebral edema. However, stroke should also be suspected when focal neurological deficits are apparent, because children with hyperglycemia and DKA are prone to thrombosis. We report three cases of pediatric stroke associated with new onset type 1 diabetes mellitus (T1DM). The first case presented with sinovenous thrombosis, and the other two cases presented in DKA and had a late diagnosis of ischemic stroke following neurological deterioration. Our recent experiences and review of the literature emphasize the importance of early diagnosis, investigation, and treatment for patients that present with new onset T1DM and stroke.