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In search of endocrine progenitor/stem cells in the human pancreas
Author(s) -
Hayek Alberto
Publication year - 2004
Publication title -
pediatric diabetes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.678
H-Index - 75
eISSN - 1399-5448
pISSN - 1399-543X
DOI - 10.1111/j.1399-543x.2004.00081.x
Subject(s) - endocrine system , progenitor cell , enteroendocrine cell , stem cell , medicine , pancreas , cell , progenitor , identification (biology) , computational biology , bioinformatics , endocrinology , biology , microbiology and biotechnology , hormone , genetics , botany
Motives to isolate endocrine precursor cells vary between clinical and basic research needs. In our case, the object has been to identify cell populations that could be used for cell replacement in situations of β‐cell deficiency, such as type 1 diabetes. Initially, as was the case with most laboratories oriented toward translational islet research, experimentation was geared more toward cell replication than to the identification and isolation of putative endocrine cell precursors.