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B artonella henselae ‐mediated disease in solid organ transplant recipients: two pediatric cases and a literature review
Author(s) -
Rostad C.A.,
McElroy A.K.,
Hilinski J.A.,
Thompson M.P.,
Drew C.P.,
Denison A.M.,
Zaki S.R.,
Mahle W.T.,
Rogers J.,
Abramowsky C.R.,
Shehata B.
Publication year - 2012
Publication title -
transplant infectious disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.69
H-Index - 67
eISSN - 1399-3062
pISSN - 1398-2273
DOI - 10.1111/j.1399-3062.2012.00774.x
Subject(s) - medicine , disease , solid organ , organ transplantation , immunology , transplantation
Bartonella henselae , the etiologic agent of cat‐scratch disease, causes a well‐defined, self‐limited syndrome of fever and regional lymphadenopathy in immunocompetent hosts. In immunocompromised hosts, however, B . henselae can cause severe disseminated disease and pathologic vasoproliferation known as bacillary angiomatosis ( BA ) or bacillary peliosis. BA was first recognized in patients infected with human immunodeficiency virus. It has become more frequently recognized in solid organ transplant ( SOT ) recipients, but reports of pediatric cases remain rare. Our review of the literature revealed only one previously reported case of BA in a pediatric SOT recipient. We herein present 2 pediatric cases, one of which is the first reported case of BA in a pediatric cardiac transplant recipient, to our knowledge. In addition, we review and summarize the literature pertaining to all cases of B . henselae ‐mediated disease in SOT recipients.