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A case of wrist tenosynovitis caused by M ycobacterium kansasii in a renal transplant recipient
Author(s) -
Chan A.,
Findlay A.,
Abeygunasekara S.
Publication year - 2012
Publication title -
transplant infectious disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.69
H-Index - 67
eISSN - 1399-3062
pISSN - 1398-2273
DOI - 10.1111/j.1399-3062.2012.00768.x
Subject(s) - medicine , tenosynovitis , wrist , renal transplant , mycobacterium kansasii , surgery , pathology , transplantation , tuberculosis , mycobacterium
Mycobacterial infection in an organ transplant recipient is a diagnostic and therapeutic challenge. Diagnosis is often delayed, resulting in significant morbidity. Anti‐microbial chemotherapy needs careful selection to prevent potentially significant complications, such as organ rejection and dose‐related toxicities. We present the case of a 61‐year‐old C aucasian male kidney transplant recipient with chronic tenosynovitis of the left wrist. Histological findings of the synovial biopsy revealed multinucleated giant cell epithelioid granuloma. Culture of synovial fluid grew M ycobacterium kansasii . Treatment with rifampicin, ethambutol, and clarithromycin proved curative, but the patient developed irreversible ethambutol‐related optic neuritis.