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Fatal Burkholderia gladioli infection misidentified as Empedobacter brevis in a lung transplant recipient with cystic fibrosis
Author(s) -
Brizendine K.D.,
Baddley J.W.,
Pappas P.G.,
Leon K.J.,
Rodriguez J.M.
Publication year - 2012
Publication title -
transplant infectious disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.69
H-Index - 67
eISSN - 1399-3062
pISSN - 1398-2273
DOI - 10.1111/j.1399-3062.2012.00726.x
Subject(s) - medicine , cystic fibrosis , bacteremia , pneumonia , empyema , lung transplantation , lung , lung abscess , abscess , pathology , surgery , microbiology and biotechnology , antibiotics , biology
Data describing the risk of lung transplantation ( LT ), clinical features, and outcomes of patients with cystic fibrosis ( CF ) infected with Burkholderia gladioli are limited. Herein, we report a case of disseminated B. gladioli infection characterized by bacteremia, necrotizing pneumonia, lung abscess, and empyema in a lung transplant recipient with CF , highlight the importance of accurate microbiological identification, and review published outcomes of LT in CF patients infected with B. gladioli , which include cases of pneumonia, tracheobronchitis, bacteremia, and abscesses, and demonstrate an all‐cause 1‐year mortality of approximately 23%, often after combined medical and surgical treatment.