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Quantitation of human herpesvirus‐6 ( HHV ‐6) DNA in a cord blood transplant recipient with chromosomal integration of HHV ‐6
Author(s) -
Kobayashi D.,
Kogawa K.,
Imai K.,
Tanaka T.,
Hiroi S.,
Satoh H.,
TanakaTaya K.,
oyama S.
Publication year - 2011
Publication title -
transplant infectious disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.69
H-Index - 67
eISSN - 1399-3062
pISSN - 1398-2273
DOI - 10.1111/j.1399-3062.2011.00693.x
Subject(s) - human herpesvirus 6 , medicine , cord blood , polymerase chain reaction , transplantation , dna , immunology , virology , herpesviridae , virus , gene , biology , genetics , viral disease
Chromosomal integration of the human herpesvirus‐6 ( HHV ‐6) genome ( CIHHV ‐6) is an important consideration if HHV ‐6 DNA is detected during the course of transplantation. A 4‐year‐old girl with refractory anemia with excess blasts type‐2 was diagnosed with CIHHV ‐6 before a cord blood transplantation. HHV ‐6 DNA was serially quantitated by polymerase chain reaction assay in the transplant period. The possibility of HHV ‐6 reactivation in a transplant recipient with CIHHV ‐6 was suspected in our case.