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Bacterial contamination of organ graft preservation solution and infection after transplantation
Author(s) -
Sauget M.,
Verdy S.,
Slekovec C.,
Bertrand X.,
Talon D.
Publication year - 2011
Publication title -
transplant infectious disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.69
H-Index - 67
eISSN - 1399-3062
pISSN - 1398-2273
DOI - 10.1111/j.1399-3062.2010.00597.x
Subject(s) - medicine , contamination , transplantation , graft rejection , intensive care medicine , microbiology and biotechnology , surgery , ecology , biology
M. Sauget, S. Verdy, C. Slekovec, X. Bertrand, D. Talon. Bacterial contamination of organ graft preservation solution and infection after transplantation.
Transpl Infect Dis 2011: 13: 331–334. All rights reserved Abstract: Infectious complications represent a major cause of morbidity and mortality in patients with organ transplantation. Contamination of preservation solution (PS) can lead to life‐threatening complications in the recipients. For a 3‐year period, we investigated the bacterial contamination of both PSs and graft fragments, recipient infections, and explored the link between them. In total 137 organs were transplanted, and 131 organ and perfusate cultures out of 426 tested (30.8%) gave a positive bacterial culture, mainly with coagulase‐negative staphylococci. Overall, 80 recipients out of 137 (58.4%) had at least 1 infection during the 4‐month post‐graft surveillance period. Twelve recipients had an infection with the same bacterial species that was recovered in the corresponding graft. However, based on pulsed‐field gel electrophoresis typing results, only 1 case was very likely cross‐transmitted via the transplantation.