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Aspergillus endocarditis in lung transplant recipients: case report and literature review
Author(s) -
Lázaro M.,
Ramos A.,
Ussetti P.,
Asensio A.,
Laporta R.,
Muñez E.,
SánchezRomero I.,
Tejerina E.,
Burgos R.,
Moñivas V.,
Varela A.
Publication year - 2011
Publication title -
transplant infectious disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.69
H-Index - 67
eISSN - 1399-3062
pISSN - 1398-2273
DOI - 10.1111/j.1399-3062.2010.00589.x
Subject(s) - medicine , endocarditis , cystic fibrosis , aspergillus fumigatus , lung , aspergillus , infective endocarditis , lung transplantation , antifungal , lung disease , surgery , dermatology , microbiology and biotechnology , immunology , biology
M. Lázaro, A. Ramos, P. Ussetti, A. Asensio, R. Laporta, E. Muñez, I. Sánchez‐Romero, E. Tejerina, R. Burgos, V. Moñivas, A. Varela. Aspergillus endocarditis in lung transplant recipients: case report and literature review.
Transpl Infect Dis 2011: 13 : 186–191. All rights reserved Abstract: We present a case of endocarditis caused by Aspergillus in a lung transplant (LT) patient and review 6 previously reported cases. All cases were caused by Aspergillus fumigatus . Five patients (71%) were transplanted due to cystic fibrosis. None of the patients had any previously known valvular heart disease. The time that elapsed between LT surgery and the diagnosis of Aspergillus endocarditis was 8±6 months. Large peripheral emboli were observed in 6 patients (85%); blood cultures were negative in all. Transthoracic echocardiography did not detect the presence of vegetations in 3 patients (43%); the vegetations measured >1.5 cm in all cases. Five patients (71%) died from disseminated disease. Both survivors underwent combined therapy with antifungal drugs and surgical treatment.