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Immune reconstitution inflammatory syndrome associated with Aspergillus terreus pulmonary infection in an autologous stem cell transplant recipient
Author(s) -
Antinori S.,
Corbellino M.,
Necchi A.,
Corradini P.,
Vismara C.,
Montefusco V.,
Gianni A.M.
Publication year - 2010
Publication title -
transplant infectious disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.69
H-Index - 67
eISSN - 1399-3062
pISSN - 1398-2273
DOI - 10.1111/j.1399-3062.2009.00460.x
Subject(s) - medicine , aspergillus terreus , immune reconstitution inflammatory syndrome , immunology , immune system , aspergillus , neutropenia , stem cell , aspergillosis , lung , microbiology and biotechnology , biology , chemotherapy , genetics , human immunodeficiency virus (hiv) , viral load , antiretroviral therapy
S. Antinori, M. Corbellino, A. Necchi, P. Corradini, C. Vismara, V. Montefusco, A.M. Gianni. Immune reconstitution inflammatory syndrome associated with Aspergillus terreus pulmonary infection in an autologous stem cell transplant recipient.
Transpl Infect Dis 2010: 12: 64–68. All rights reserved Abstract: We describe an autologous stem cell transplant recipient who developed immune reconstitution inflammatory syndrome (IRIS) associated with Aspergillus terreus invasive pulmonary infection after recovery from neutropenia. Clinical and radiological worsening of pulmonary invasive aspergillosis coincident with a robust decline of serum galactomannan values and rising neutrophil counts should be interpreted as IRIS and should not require changes to antifungal therapy.