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Cryptococcal infection presenting as cellulitis in a renal transplant recipient
Author(s) -
Orsini J.,
Nowakowski J.,
Delaney V.,
Sakoulas G.,
Wormser G.P.
Publication year - 2009
Publication title -
transplant infectious disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.69
H-Index - 67
eISSN - 1399-3062
pISSN - 1398-2273
DOI - 10.1111/j.1399-3062.2008.00352.x
Subject(s) - medicine , cellulitis , cryptococcus neoformans , renal transplant , opportunistic infection , intensive care medicine , cryptococcosis , complication , transplantation , antimicrobial , empiric therapy , soft tissue , cryptococcus , organ transplantation , immunosuppression , dermatology , immunology , pathology , human immunodeficiency virus (hiv) , surgery , microbiology and biotechnology , viral disease , biology , alternative medicine
Opportunistic infections of skin and soft tissue represent a rare but serious complication following solid organ transplantation. We report a case of severe soft tissue infection caused by Cryptococcus neoformans in a renal transplant recipient. Physicians need to consider the possibility of opportunistic pathogens when managing infections in immunocompromised hosts, especially when symptoms persist despite seemingly appropriate empiric antimicrobial therapy. Tissue sampling for histological and microbiological evaluation is usually necessary to establish a diagnosis.