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Rotavirus enteritis in solid organ transplant recipients: an underestimated problem?
Author(s) -
Stelzmueller I.,
Wiesmayr S.,
Swenson B.R.,
Biebl M.,
Goegele H.,
Margreiter R.,
Bonatti H.
Publication year - 2007
Publication title -
transplant infectious disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.69
H-Index - 67
eISSN - 1399-3062
pISSN - 1398-2273
DOI - 10.1111/j.1399-3062.2007.00251.x
Subject(s) - medicine , enteritis , solid organ , diarrhea , rotavirus , retrospective cohort study , organ transplantation , transplantation , complication , young adult , gastroenterology , pediatrics
Background. Diarrhea in solid organ transplantation can be a complication with a high morbidity and mortality. Rotavirus (RV) infection normally occurs in children up to 3 years of age and often presents with severe diarrhea; however, it can also affect adults. We investigated the prevalence and outcome of RV infections in both adult and pediatric patients after solid organ transplantation. Patients and methods. Retrospective analysis of RV‐related enteritis in solid organ transplant recipients with a minimum of a 1‐year follow‐up from a single center between 2000 and 2004. Results. Within our cohort of 1303 solid organ transplants, RV infection was observed in 19 patients (1.5%); 14 of these were liver recipients. Infection was most prevalent among pediatric liver recipients, with 52% (11/21) of the children affected. Five adults acquired the infection during their initial hospitalization. Two adult patients had to be readmitted following late‐onset RV infection. In all cases, infection was self‐limiting, but led to prolonged hospitalization because of significant loss of fluids and electrolytes. Conclusions. RV enteritis is a common infection in pediatric solid organ recipients but may also affect adult patients.