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Mycobacterium avium complex infection in kidney transplant patients
Author(s) -
Haas S.,
Scully B.,
Cohen D.,
Radhakrishnan J.
Publication year - 2005
Publication title -
transplant infectious disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.69
H-Index - 67
eISSN - 1399-3062
pISSN - 1398-2273
DOI - 10.1111/j.1399-3062.2005.00090.x
Subject(s) - medicine , mycobacterium avium complex , kidney transplant , kidney transplantation , mycobacterium , microbiology and biotechnology , kidney , immunology , pathology , tuberculosis , biology
Mycobacterium avium complex (MAC) infections have been reported rarely in renal transplant patients. Consequently the clinical course and optimal treatment of these patients are not well understood. We present 3 patients with MAC infections after receiving a renal transplant (2 with generalized and 1 with localized infection). All patients were treated with combination antibiotic therapy and reduction of immunosuppression. One patient experienced clinical control of disease but a mild cellular rejection that was successfully treated with high‐dose corticosteroids. One patient died of disseminated MAC infection. The patient with localized infection died of unrelated causes. In summary, MAC infection, although rare in renal transplant patients, may respond to combination antimicrobial therapy and reduction of immunosuppression.