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The oxidation of cytosolic NAD(P)H by external NAD(P)H dehydrogenases in the respiratory chain of plant mitochondria
Author(s) -
Møller Ian M.
Publication year - 1997
Publication title -
physiologia plantarum
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.351
H-Index - 146
eISSN - 1399-3054
pISSN - 0031-9317
DOI - 10.1111/j.1399-3054.1997.tb03457.x
Subject(s) - nad+ kinase , mitochondrion , cytosol , respiratory chain , chemistry , biochemistry , mitochondrial respiratory chain , enzyme
The respiratory chain of plant mitochondria differs from that in mammalian mitochondria by containing several rotenone‐insensitive NAD(P)H dehydrogenases. Two of these are located on the outer, cytosolic surface of the inner membrane. One is specific for NADH, the other for NADPH. Only the latter is inhibited by diphenyleneiodonium (DPI). Both of these enzymes are normally dependent upon Ca 2+ for activity and this constitutes a potentially important mechanism by which the cell can regulate the oxidation of cytosolic NAD(P)H via the concentration of free Ca 2+ . This and other potential regulatory mechanisms such as the substrate concentration and polyamines are discussed.