Premium
The effect of butyrate on cell cycle progression in Allium cepa root meristems
Author(s) -
Lanzagorta J. M. Alicia,
Torre Consuelo,
Aller Patricio
Publication year - 1988
Publication title -
physiologia plantarum
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.351
H-Index - 146
eISSN - 1399-3054
pISSN - 0031-9317
DOI - 10.1111/j.1399-3054.1988.tb06378.x
Subject(s) - butyrate , meristem , cell cycle , allium , mitosis , sodium butyrate , cell , microbiology and biotechnology , cell growth , biochemistry , biology , cell division , chemistry , biophysics , botany , shoot , fermentation , gene
Sodium butyrate at 4 m M and above blocked cell proliferation in root meristems of Allium cepa L. bulbs. Cytophotometric determinations in asynchronously growing cells, as well as cycle kinetics in synchronous binucleate cells. indicated that blocking took place at mid‐G 1 and at, or close to, the S/G 2 border. Cell progression through S phase and mitosis was little affected. The cell cycle blockage induced by 6 m M butyrate was reversible when the drug was applied for periods of time not exceeding 12 h. Butyrate did not affect nucleic acid and protein synthesis activities, though its action on the cell cycle ressembled that produced by translation inhibitors.