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Effect of kidney transplantation on heart conduction disturbances in children treated with chronic hemodialysis – A pilot study
Author(s) -
PolakJonkisz Dorota,
LaszkiSzcząchor Krystyna,
Sobieszczańska Małgorzata,
Makulska Irena,
Pilecki Witold,
Rusiecki Lesław,
Zwolińska Danuta
Publication year - 2011
Publication title -
pediatric transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 69
eISSN - 1399-3046
pISSN - 1397-3142
DOI - 10.1111/j.1399-3046.2011.01588.x
Subject(s) - medicine , transplantation , hemodialysis , cardiology , kidney transplantation , left ventricular hypertrophy , heart transplantation , blood pressure
Polak‐Jonkisz D, Laszki‐Szcząchor K, Sobieszczańska M, Makulska I, Pilecki W, Rusiecki L, Zwolińska D. Effect of kidney transplantation on heart conduction disturbances in children treated with chronic hemodialysis – A pilot study.
Pediatr Transplantation 2011: 15: 835–843. © 2011 John Wiley & Sons A/S. Abstract: Aim of the study was to assess the effect of KT on heart conduction in HD children. Non‐invasive electrocardiographic method of BSPM was used. Isochrone maps, presenting a VAT distribution, were taken from eight HD patients and 26 normal subjects. Patients were divided into two groups: I – three children were HD <12 months prior to KT; II – five children were HD >12 months prior to KT. After KT, the groups were marked as IP and IIP. Serum iPTH and phosphate levels were significantly higher in both HD groups than in controls, with a considerable normalization after transplantation. HD patients demonstrated neither conduction abnormalities on ECG nor left ventricular hypertrophy. Group‐mean VAT maps revealed: I and II – similar patterns of complete LBBB; IP – partial normalization to a pattern of anterior fascicle block; IIP – preserved pattern of LBBB. Intraventricular conduction disturbances found in HD children using BSPM were alleviated by KT. Short HD therapy increases a chance of conduction disturbances regression after KT, contrary to the longer HD treatment. BSPM is more sensitive than standard ECG in detecting heart conduction impairments in the HD patients.