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Good outcome of kidney transplants in recipients of young donors: a NAPRTCS data analysis
Author(s) -
Moudgil Asha,
Martz Karen,
Stablein Donald M.,
Puliyanda Dechu P.
Publication year - 2011
Publication title -
pediatric transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 69
eISSN - 1399-3046
pISSN - 1397-3142
DOI - 10.1111/j.1399-3046.2010.01432.x
Subject(s) - medicine , outcome (game theory) , kidney transplantation , kidney transplant , kidney , intensive care medicine , surgery , mathematics , mathematical economics
Moudgil A, Martz K, Stablein DM, Puliyanda DP. Good outcome of kidney transplants in recipients of young donors: a NAPRTCS data analysis.
Pediatr Transplantation 2011: 15:167–171. © 2010 John Wiley & Sons A/S. Abstract: NAPRTCS data were analyzed to assess outcome of TX recipients from YDs (<5 yr) in comparison with IDs (6–35 yr) and ODs (36–55 yr). Of 9854 TX in NAPRTCS (1987–2003), 469 were YD. Patient survival (PS) and graft survival (GS) were compared between DD TX after 1995; 81YD, 1324 ID, and 429 OD and eGFR were compared among functioning grafts (YD 31, ID 439, OD 174) at three yr. PS was comparable in all groups; GS at one, two, and three yr in TX of YD (91.1%, 83.8%, 79.7%), ID (93.5%, 89.7%, 83.6%), and OD (92.2%, 87.2%, 82.4%) was comparable. The eGFR in YD was comparable to ID but better than OD (86.5 vs. 79.7 vs. 67.2 mL/min/1.73 m 2 , p 0.139 and <0.0003). Primary graft non‐function was more frequent in TX from YD than ID and OD (3.7% vs. 0.3 and 0.7%, p = 0.004); the incidence of vascular thrombosis was similar. The aforementioned data show that pediatric recipients of YD had equivalent patient and graft survival. Although primary graft non‐function was higher, eGFR of functioning grafts was comparable to ID. With further improvements in care, kidneys from YD may present a viable option for transplantation.