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Intracoronary administration of autologous mesenchymal stem cells in a critically ill patient with dilated cardiomyopathy
Author(s) -
Zeinaloo Aliakbar,
Zanjani Keyhan S.,
Bagheri Mohammad M.,
MohyeddinBonab Mandana,
Monajemzadeh Maryam,
Arjmandnia Mohammad H.
Publication year - 2011
Publication title -
pediatric transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 69
eISSN - 1399-3046
pISSN - 1397-3142
DOI - 10.1111/j.1399-3046.2010.01366.x
Subject(s) - medicine , mesenchymal stem cell , dilated cardiomyopathy , critically ill , cardiomyopathy , stem cell , transplantation , cardiology , heart failure , pathology , biology , genetics
Zeinaloo AA, Zanjani KS., Bagheri MM., Mohyeddin‐Bonab M, Monajemzadeh M, Arjmandnia MH. Intracoronary administration of autologous mesenchymal stem cells in a critically ill patient with dilated cardiomyopathy.
Pediatr Transplantation 2011: 15: E183–E186. © 2011 John Wiley & Sons A/S. Abstract: Relatively high prevalence of dilated cardiomyopathy in children, unfavorable response to traditional drug therapy, and limitations in heart transplantation call for new therapeutic options. Stem cell therapy can be promising in children suffering from this disease. The presented case documents that intracoronary injection of autologous bone marrow‐derived mesenchymal stem cells in a boy with progressive dilated cardiomyopathy is feasible and safe. Furthermore, it may positively influence functional class, quality of life, and echocardiographic indices of cardiac function.