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Indications for combined liver and kidney transplantation in children
Author(s) -
Chava Srinivas P.,
Singh Balbir,
Pal Sujoy,
Dhawan Anil,
Heaton Nigel D.
Publication year - 2009
Publication title -
pediatric transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 69
eISSN - 1399-3046
pISSN - 1397-3142
DOI - 10.1111/j.1399-3046.2008.01046.x
Subject(s) - medicine , liver transplantation , kidney , transplantation , kidney transplantation , intensive care medicine , pediatrics
A significant number of patients awaiting liver transplantation have associated renal failure and renal dysfunction is associated with increased morbidity and mortality after LT. There has been a recent increase in the number of CLKT in adults. The common indications for CLKT in children are different from those of adults and include metabolic diseases affecting the kidney with or without liver dysfunction and congenital developmental abnormalities affecting both organs. The results are generally encouraging among these groups of patients. Early evaluation and listing of patients before they become severely ill or have major systemic manifestations of their metabolic problem are important.