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Combined liver‐kidney transplantation in children: Indications and outcome
Author(s) -
Sutherland Scott M.,
Alexander Steven R.,
Sarwal Minnie M.,
Berquist William E.,
Concepcion Waldo
Publication year - 2008
Publication title -
pediatric transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 69
eISSN - 1399-3046
pISSN - 1397-3142
DOI - 10.1111/j.1399-3046.2008.01041.x
Subject(s) - medicine , liver transplantation , kidney transplantation , transplantation , outcome (game theory) , kidney , intensive care medicine , mathematics , mathematical economics
Although it remains a relatively infrequent procedure in children, CLKT has become a viable option for a select group of pediatric patients with severe liver and kidney disease. Most are performed for rare primary diseases such as PH1, but a selected few are performed in the setting of concomitant hepatic and renal failure of uncertain etiology and prognosis. This article reviews the indications for and outcomes following CLKT in children. While it focuses on the specific primary diseases which impact liver and kidney function simultaneously, it addresses the indications based on concomitant hepatic and renal failure, such as seen in the hepatorenal syndrome, as well.