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Continued complete remission without systemic therapy for isolated testicular relapse after bone marrow transplantation in a boy with acute lymphoblastic leukemia
Author(s) -
Kodama Yuichi,
Okamoto Yasuhiro,
Ijichi Osamu,
Shinkoda Yuichi,
Nishikawa Takuro,
Tanabe Takayuki,
Yoshioka Takako,
Tashiro Yukie,
Mougi Hiroyuki,
Kawano Yoshifumi
Publication year - 2009
Publication title -
pediatric transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 69
eISSN - 1399-3046
pISSN - 1397-3142
DOI - 10.1111/j.1399-3046.2008.01023.x
Subject(s) - medicine , orchiectomy , chemotherapy , lymphoblastic leukemia , complete remission , leukemia , bone marrow transplantation , surgery , bone marrow , transplantation
ITR after BMT in cases of acute lymphoblastic leukemia is relatively rare. Treatment for ITR after BMT generally consists of a combination of local irradiation, orchiectomy, and systemic chemotherapy. However, the effectiveness of these modalities has not been established. Both irradiation and systemic chemotherapy including a second transplantation would result in additional toxicity. In this report we describe a boy with ITR 91 months after BMT who has remained in complete remission more than two yr after a unilateral orchiectomy. We did not treat this patient with systemic chemotherapy, as his ITR developed very late. Our experience suggests that orchiectomy alone is a reasonable option for very late ITR after BMT.