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Successful treatment of a child having generalized Kaposi's sarcoma after living donor liver transplantation with conversion to sirolimus
Author(s) -
Yuksekkaya Hasan A.,
Arikan Cigdem,
Yazici Ayse,
Baran Masallah,
Aydogdu Sema,
Kilic Murat
Publication year - 2009
Publication title -
pediatric transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 69
eISSN - 1399-3046
pISSN - 1397-3142
DOI - 10.1111/j.1399-3046.2008.00944.x
Subject(s) - medicine , sirolimus , sarcoma , in vivo , transplantation , in vitro , liver transplantation , immunosuppression , oncology , pathology , biochemistry , chemistry , microbiology and biotechnology , biology
SRL is a new and potent immunosuppressive agent that has been successfully introduced in organ transplantation. In contrast to other immunosuppressive agents, SRL has a potent antitumor activity both in vitro and in vivo . Herein, we report a child with Kaposi’s sarcoma that was diagnosed 30 months after LDLT and treated successfully with only conversion to SRL monotherapy. KS regressed completely at the end of the first month and remained in remission during 28 months follow‐up.