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Aspergillus fumigatus endocarditis in a pediatric liver transplant recipient: Favorable outcome without cardiac surgery
Author(s) -
Mourier Olivia,
Durand Philippe,
Lambert Virginie,
Bretagne Stéphane,
Maurage Chantal,
Branchereau Sophie,
Bernard Olivier,
Jacquemin Emmanuel
Publication year - 2009
Publication title -
pediatric transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 69
eISSN - 1399-3046
pISSN - 1397-3142
DOI - 10.1111/j.1399-3046.2008.00929.x
Subject(s) - medicine , aspergillus fumigatus , aspergillosis , endocarditis , liver transplantation , antifungal , organ transplantation , aspergillus , surgery , transplantation , cardiac surgery , immunology , microbiology and biotechnology , dermatology , biology
Transplant recipients are very susceptible to invasive aspergillosis, which increases mortality rate. Disseminated aspergillosis in the liver transplant recipient can affect virtually any organ and endocarditis is often lethal despite cardiac surgery and antifungal therapy. We report the case of a eight‐month‐old girl who presented with Aspergillus fumigatus endocarditis 18 days after liver transplantation that was successfully treated by a combination of antifungal drugs associated to a low dosage of immunosuppressive therapy.