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Adenovirus‐associated hemorrhagic cystitis in a pediatric renal transplant recipient
Author(s) -
Keswani Mahima,
Moudgil Asha
Publication year - 2007
Publication title -
pediatric transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 69
eISSN - 1399-3046
pISSN - 1397-3142
DOI - 10.1111/j.1399-3046.2007.00736.x
Subject(s) - hemorrhagic cystitis , cidofovir , medicine , immunosuppression , bk virus , renal transplant , transplantation , immunology , kidney transplantation , virus , hematopoietic stem cell transplantation
Adenovirus infection has been associated with the development of hemorrhagic cystitis in bone marrow transplant recipients. However, limited information exists regarding adenovirus‐associated hemorrhagic cystitis in solid organ transplantation, especially in renal transplant recipients. In most cases, the disease is self‐limited. However, some patients may have a protracted course. Although no particular antiviral agent has been identified as the gold standard of therapy, cidofovir has been found to be effective in a number of bone marrow transplant recipients. In this study, we report a five‐yr‐old boy who presented with adenovirus‐associated hemorrhagic cystitis 68 days after renal transplant and was successfully treated with reduction of immunosuppression and an intermediate dose of intravenous cidofovir.