Nitazoxanide or CD3+/CD4+ lymphocytes for recovery from severe  Cryptosporidium  infection after allogeneic bone marrow transplant? | Zendy

Faraci M. | Zendy; Cappelli B. | Zendy; Morreale G. | Zendy; Lanino E. | Zendy; Moroni C. | Zendy; Bandettini R. | Zendy; Terranova M. P. | Zendy; Di Martino D. | Zendy; Coccia C. | Zendy; Castagnola E. | Zendy

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Nitazoxanide or CD3+/CD4+ lymphocytes for recovery from severe Cryptosporidium infection after allogeneic bone marrow transplant?

Author(s) -

Faraci M.,

Cappelli B.,

Morreale G.,

Lanino E.,

Moroni C.,

Bandettini R.,

Terranova M. P.,

Di Martino D.,

Coccia C.,

Castagnola E.

Publication year - 2007

Publication title -

pediatric transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.457

H-Index - 69

eISSN - 1399-3046

pISSN - 1397-3142

DOI - 10.1111/j.1399-3046.2006.00622.x

Subject(s) - nitazoxanide , medicine , cryptosporidium , immunology , cryptosporidium parvum , gastroenterology , virology , feces , microbiology and biotechnology , biology

We describe a case of Cryptosporidium infection occurring in a child after allogeneic SCT for acute non‐lymphoblastic leukemia. This patient presented an intestinal, biliar, and pancreatic Cryptosporidium disease associated with an intestinal aGvHD. The increase in CD3+/CD4+ cells secondary to the reduction of steroid therapy associated with the improvement of aGvHD and the use of antiparasitic treatments (especially nitazoxanide) improved the infection‐related symptoms and led to a complete clearance of the Cryptosporidium.

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