Chimerism in a child with severe combined immunodeficiency: A case report | Zendy

Aureli Anna | Zendy; Piancatelli Daniela | Zendy; Monaco Palmina I. | Zendy; Ozzella Giuseppina | Zendy; Canossi Angelica | Zendy; Piazza Antonina | Zendy; Isacchi Giancarlo | Zendy; Caniglia Maurizio | Zendy; Adorno Domenico | Zendy

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Chimerism in a child with severe combined immunodeficiency: A case report

Author(s) -

Aureli Anna,

Piancatelli Daniela,

Monaco Palmina I.,

Ozzella Giuseppina,

Canossi Angelica,

Piazza Antonina,

Isacchi Giancarlo,

Caniglia Maurizio,

Adorno Domenico

Publication year - 2006

Publication title -

pediatric transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.457

H-Index - 69

eISSN - 1399-3046

pISSN - 1397-3142

DOI - 10.1111/j.1399-3046.2006.00568.x

Subject(s) - severe combined immunodeficiency , medicine , hematopoietic stem cell transplantation , immunodeficiency , immunologic deficiency syndromes , primary immunodeficiency , lymphocyte , transplantation , immunology , pediatrics , hematopoietic cell , stem cell , peripheral blood , immunodeficiency syndrome , haematopoiesis , immune system , genetics , biology , gene

Severe combined immunodeficiency (SCID) represents a group of rare, sometimes fatal, congenital disorders in which there is a combined absence of T‐lymphocyte and B‐lymphocyte function. Children with SCID die within two years of age, if untreated. The effective treatment for SCID is a hematopoietic stem cell transplantation (HSCT). It has been repeatedly described that in peripheral blood of infants with SCID maternal T cells can be found. Here we report a case of blood chimerism in a one‐year‐old boy with SCID.

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