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Reversal of tacrolimus‐related hypertrophic obstructive cardiomyopathy 5 years after kidney transplant in a 6‐year‐old recipient
Author(s) -
Jarzembowski Tomasz M.,
John Eunice,
Panaro Fabrizio,
Manzelli Antonio,
Cabrera Antonio,
Greco Andreas,
Varga Peter,
Sankary Howard,
Testa Giuliano,
Benedetti Enrico
Publication year - 2005
Publication title -
pediatric transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 69
eISSN - 1399-3046
pISSN - 1397-3142
DOI - 10.1111/j.1399-3046.2005.00260.x
Subject(s) - medicine , tacrolimus , hypertrophic cardiomyopathy , obstructive cardiomyopathy , cardiology , kidney transplant , kidney transplantation , kidney , transplantation
Hypertrophic obstructive cardiomyopathy (HOCM) is an unusual but serious side‐effect of tacrolimus (TAC) based immunosuppression primarily affecting pediatric patients after solid organ transplant. TAC‐induced HOCM has already been described in patients after liver, bowel and heart transplant shortly after the procedure. Herein, we present the first case report of TAC‐induced HOCM in a young renal transplant recipient 5 yr after renal transplant. The condition was diagnosed by ECHO and EKG and successfully treated by discontinuation of TAC followed by conversion to cyclosporine (CsA).