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An evaluation of the diagnostic value of different skin tests with egg in clinically egg‐allergic children having atopic dermatitis
Author(s) -
Hansen Tine K.,
Høst Arne,
BindslevJensen Carsten
Publication year - 2004
Publication title -
pediatric allergy and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.269
H-Index - 89
eISSN - 1399-3038
pISSN - 0905-6157
DOI - 10.1111/j.1399-3038.2004.00193.x
Subject(s) - medicine , atopic dermatitis , egg allergy , atopy , food allergy , allergy , dermatology , food allergens , patch test , oral food challenge , immunology
Skin testing is a common diagnostic procedure in food allergy, but the final diagnosis of food allergy is based on the clinical response to food challenge. We studied the value of the skin prick‐prick test (SPT), skin application food test (SAFT) and atopy patch test (APT) with fresh egg extract in diagnosing egg allergy. Ten clinically egg‐allergic children with atopic dermatitis (AD; age 10 months to 8.4 yr, mean 3.4 yr) and 10 egg‐tolerant children with and 10 without AD (age 2.4–11 yr, mean 5.5 yr) participated. In SAFT several false‐negative reactions were seen, whereas all clinically egg‐allergic children were positive in SPT and 40–60% in APT. In APT and in SPT false‐positive reactions to egg were observed. In this study comprising a small number of patients including control subjects, neither SAFT nor APT with fresh whole egg extract were able to increase the diagnostic accuracy in detecting egg‐allergic children with AD compared with SPT.