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Comparison of three immunoassays for diagnosing sensitization to latex in children with spina bifida
Author(s) -
Niggemann B.,
Michael T.,
Moers A.,
Seidel U.,
Wahl R.,
Jacobsen L,
Scheffer D.,
Wahn U.
Publication year - 1996
Publication title -
pediatric allergy and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.269
H-Index - 89
eISSN - 1399-3038
pISSN - 0905-6157
DOI - 10.1111/j.1399-3038.1996.tb00126.x
Subject(s) - medicine , spina bifida , sensitization , pediatrics , immunology
As natural rubber latex (latex) has become more widespread in our environment, physicians have become increasingly aware of the problem of possible allergic reactions. Many fatal and near‐fatal incidents have been reported (mainly during surgery) (1—3) and data has been published on groups frequently exposed to latex, such as patients with spina bifida (4—9), healthcare professionals (10—12) and occupationally exposed persons (13). The incidence of latex allergy in children seems to be increasing (14). Tests are therefore needed which can reliably detect sensitization to latex. Our aim was to compare the diagnostic accuracy of three commercial immunoassays for measuring specific IgE in serum to latex.