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Eosinophils and basophilic cells in sputum and nasal smears taken from infants and young children during acute asthma
Author(s) -
Nagayama Y.,
Odazima Y.,
Nakayama S.,
Toba T.,
Funabashi S.
Publication year - 1995
Publication title -
pediatric allergy and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.269
H-Index - 89
eISSN - 1399-3038
pISSN - 0905-6157
DOI - 10.1111/j.1399-3038.1995.tb00286.x
Subject(s) - medicine , asthma , sputum , basophilic , immunology , pathology , tuberculosis
To examine the increase in eosinophils and basophilic cells in the respiratory areas of infants and young children with asthma ( n = 111), we analyzed the numbers of eosinophils and basophilic cells in sputum and nasal smears. The number of children with eosinophilia grades of 2+ or greater (> = 11 cells/five fields in x 1000 magnification) in sputum and nasal smears, respectively, in each age group was as follows: 33% and 21% under 1 year, 59% and 64% at 1 year, and 79–80% and 75–78% at 2–3 years. An increased infiltration of basophilic cells according to age was also observed. Infiltration of these cells began earlier than the appearance of IgE antibodies to mite in blood.