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Increase in platelet count following short course therapy with recombinant alpha‐2b‐interferon in immune thrombocytopenic purpura in childhood
Author(s) -
Behrenbeck U.,
Riedel F.,
Rieger C. H. L.
Publication year - 1993
Publication title -
pediatric allergy and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.269
H-Index - 89
eISSN - 1399-3038
pISSN - 0905-6157
DOI - 10.1111/j.1399-3038.1993.tb00058.x
Subject(s) - medicine , thrombocytopenic purpura , platelet , alpha interferon , purpura (gastropod) , immunology , immune system , alpha (finance) , immune thrombocytopenia , gamma globulin , interferon , antibody , surgery , ecology , construct validity , patient satisfaction , biology
Two boys, aged three and seven years with immune thrombocytopenic purpura continued to show platelet counts below 20, 000/mm 3 inspite of treatment with high dose gammaglobulin and steroids. Alpha‐2b‐in‐terferon injections were followed by normalisation of platelet counts in both patients. No side effects were seen. Alpha‐interferon may be a safe and effective treatment for childhood‐ITP.