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Heterogeneity of IgA deficiency in childhood
Author(s) -
Pignata C.,
Monaco G.,
Ciccimarra F.
Publication year - 1991
Publication title -
pediatric allergy and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.269
H-Index - 89
eISSN - 1399-3038
pISSN - 0905-6157
DOI - 10.1111/j.1399-3038.1991.tb00178.x
Subject(s) - iga deficiency , medicine , autoantibody , immunoglobulin a , selective iga deficiency , immunology , immunoglobulin g , antibody
Fifty‐one children with total or partial IgA deficiency were compared for clinical and laboratory features. Serum IgG were higher in total IgA deficiency. Moreover, while no subject with partial IgA deficiency showed autoantibodies, 48% of the group with total IgA deficiency showed one or more autoantibodies. These data support the notion that total and partial deficiencies are two distinct entities.