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The utilization of solid organs for transplantation in the setting of infection with multidrug‐resistant organisms: an expert opinion
Author(s) -
Bishara Jihad,
Goldberg Elad,
Lev Shaul,
Singer Pierre,
Ashkenazi Tamar,
Cohen Jonathan
Publication year - 2012
Publication title -
clinical transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.918
H-Index - 76
eISSN - 1399-0012
pISSN - 0902-0063
DOI - 10.1111/j.1399-0012.2012.01693.x
Subject(s) - medicine , transplantation , asymptomatic , intensive care medicine , multiple drug resistance , organ transplantation , expert opinion , solid organ , disease , drug resistance , microbiology and biotechnology , biology
Organ transplantation remains the optimal treatment for many patients suffering from end‐stage organ disease. Increasing numbers of patients admitted to intensive care units, among them potential heart‐beating, brain‐dead organ donors, are exposed to infections with multidrug‐resistant organisms, in particular carbapenem‐resistant K lebsiella pneumoniae ( CR ‐ KP ). An extensive literature search failed to reveal any information regarding the eligibility for transplantation of organs from such donors. For this reason, in 2009, the I srael T ransplant C enter, together with the I sraeli S ociety for I nfectious D iseases, established a working group with the intention of developing a national‐specific approach to the use of these organs. In this viewpoint article, we present an algorithm based on expert opinion and our clinical experience with a donor who was found to be an asymptomatic carrier of CR ‐ KP .