Premium
Incidence and predictors of post‐reperfusion syndrome in living donor liver transplantation
Author(s) -
Chung In S.,
Kim Ha Y.,
Shin Young H.,
Ko Justin S.,
Gwak Mi S.,
Sim Woo S.,
Kim Gaab S.,
Lee SukKoo
Publication year - 2011
Publication title -
clinical transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.918
H-Index - 76
eISSN - 1399-0012
pISSN - 0902-0063
DOI - 10.1111/j.1399-0012.2011.01568.x
Subject(s) - medicine , incidence (geometry) , liver transplantation , transplantation , living donor liver transplantation , surgery , physics , optics
Chung IS, Kim HY, Shin YH, Ko JS, Gwak MS, Sim WS, Kim GS, Lee S‐K. Incidence and predictors of post‐reperfusion syndrome in living donor liver transplantation. Abstract: A characteristic pattern of hemodynamic changes that may occur in reperfusion phase of liver transplantation (LT) is known as post‐reperfusion syndrome (PRS). In this study, we determined the frequency of PRS and evaluated possible predictors of PRS. The medical records of 152 patients who underwent living donor LT were reviewed. PRS was defined as a decrease in mean arterial pressure of more than 30% from the baseline value for more than one min during the first five min after reperfusion. The frequency of PRS was determined, and patients were divided into two groups: PRS group and non‐PRS group. Donor factors, preoperative and intraoperative recipient factors, and postoperative outcomes were compared between the two groups. PRS occurred in 58 recipients (34.2%). Preoperative model for end‐stage liver disease scores of recipients and percentage of graft steatotic changes were higher in PRS group. PRS group showed higher heart rates and lower hemoglobin values preoperatively. Before reperfusion, PRS group received more transfusion and their urine output was less than that of non‐PRS group. Postoperatively, peak bilirubin during the first five d after LT was higher in PRS group. In conclusion, both severity of liver disease and graft steatosis may increase risk for PRS in LT. Further prospective studies of PRS in its relationship to outcome are indicated.