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The case of BK virus infection in which it was difficult to differentiate from acute rejection
Author(s) -
Ito Yumi,
Nishi Shinichi,
Imai Naofumi,
Yoshita Kazuhiro,
Saito Kazuhide,
Nakagawa Yuki,
Takahashi Kota,
Narita Ichiei
Publication year - 2011
Publication title -
clinical transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.918
H-Index - 76
eISSN - 1399-0012
pISSN - 0902-0063
DOI - 10.1111/j.1399-0012.2011.01481.x
Subject(s) - medicine , bk virus , prednisone , plasmapheresis , discontinuation , mycophenolate , kidney transplantation , transplantation , biopsy , nephropathy , immunosuppression , polyomavirus infections , immunology , gastroenterology , pathology , surgery , antibody , diabetes mellitus , endocrinology
Ito Y, Nishi S, Imai N, Yoshita K, Saito K, Nakagawa Y, Takahashi K, Narita I. The case of BK virus infection in which it was difficult to differentiate from acute rejection.
Clin Transplant 2011: 25 (Suppl. 23): 44–48.
© 2011 John Wiley & Sons A/S. Abstract: BK virus (BKV) nephropathy is one of the major causes of allograft dysfunction or graft loss in kidney transplant recipients. Early diagnosis and timely reduction in immunosuppressant is important for proper treatment. We report a 35‐yr‐old male case of cadaveric renal transplantation with BK viral related tubulointerstitial nephritis complicated by acute rejection. The diagnostic biopsy showed severe inflammatory infiltrates, tubulitis, and peritubular capillaritis. Discontinuation of mycophenolate mofetil, prednisone pulse therapy, and r‐globulin was successful in relieving allograft dysfunction.