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Outcomes of surgical repair of bile leaks and strictures after adult‐to‐adult living donor liver transplant
Author(s) -
Melcher Marc L.,
Freise Chris E.,
Ascher Nancy L.,
Roberts John P.
Publication year - 2010
Publication title -
clinical transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.918
H-Index - 76
eISSN - 1399-0012
pISSN - 0902-0063
DOI - 10.1111/j.1399-0012.2010.01289.x
Subject(s) - medicine , liver transplantation , living donor liver transplantation , surgery , general surgery , transplantation
Melcher ML, Freise CE, Ascher NL, Roberts JP. Outcomes of surgical repair of bile leaks and strictures after adult‐to‐adult living donor liver transplant.
Clin Transplant 2010: 24: E230–E235. © 2010 John Wiley & Sons A/S. Abstract: We sought to determine factors that predict the successful surgical repair of biliary complications after adult living donor liver transplantation (ALDLT). Methods: Records of 82 consecutive ALDLT right lobe recipients were reviewed. Operations were performed on 19 recipients for biliary complications. Post‐operative biliary complications were analyzed. Fisher’s exact test was used to identify variables that correlated with successful surgical repair. Results: A total of 29 recipients had biliary complications, of which 19 had a surgical repair. The five recipients, operated on for a stricture without history of leaks, did not develop further complications. However, nine of 14 with a history of a leak developed further complications after surgical repair (p‐value = 0.044). All five who presented with a biliary complication more than 100 d after transplant had successful surgical repair; however, nine out of 13 who presented within 57 d had additional complications after repair. Conclusions: Operations for strictures after ALDLT are more successful than operations for leaks. Recipients with isolated biliary strictures after ALDLT can be managed surgically; however, recipients with history of a leak often require additional interventions after surgical repair.