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A case of renal transplantation with granulomatous nephritis and arteritis associated with Pseudomonous aeruginosa infection
Author(s) -
Koike Junki,
Yamaguchi Yutaka,
Horita Shigeru,
Sannomiya Akihito,
Fuchinoue Shohei,
Kohno Midori
Publication year - 2007
Publication title -
clinical transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.918
H-Index - 76
eISSN - 1399-0012
pISSN - 0902-0063
DOI - 10.1111/j.1399-0012.2007.00714.x
Subject(s) - medicine , interstitial nephritis , nephritis , transplantation , glomerulonephritis , arteritis , pseudomonas aeruginosa , urinary system , kidney transplantation , pathology , renal biopsy , vasculitis , biopsy , kidney , gastroenterology , disease , biology , bacteria , genetics
A case with graft function failure due to granulomatous interstitial nephritis and arteritis probably associated with a urinary tract infection by Pseudomonas aeruginosa within two months of kidney transplantation is reported. The recipient was a 42‐yr‐old male who had end‐stage renal disease associated with chronic glomerulonephritis. He received a kidney transplant that was donated from a 54‐yr‐old male who died because of a subarachnoid hemorrhage. On the 60th day after operation, graft function failure occurred. A biopsy specimen showed granulomatous interstitial nephritis and vasculitis. At the same time, P. aeruginosa was detected by urine culture. The graft function is improved by treatment with the antibiotic faropenem for the urinary tract infection. On the basis of these clinical features, it was suggested that the present case developed granulomatous interstitial nephritis and arteritis associated with urinary tract infection by P . aeruginosa .