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No relation between apolipoprotein E alleles and obstructive sleep apnea
Author(s) -
Saarelainen Seppo,
Lehtimäki Terho,
Kallonen Eija,
Laasonen Kirsi,
Poussa Tuija,
Nieminen Markku M
Publication year - 1998
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/j.1399-0004.1998.tb02663.x
Subject(s) - obstructive sleep apnea , apolipoprotein e , allele , medicine , risk factor , genotype , apolipoprotein b , sleep (system call) , disease , sleep apnea , endocrinology , cardiology , genetics , biology , gene , cholesterol , computer science , operating system
Apolipoprotein E (ApoE) is a genetic risk factor influencing the development of cardiovascular diseases and Alzheimer's disease. Patients with obstructive sleep apnea (OSA) suffer an excess mortality and morbidity from cardiovascular diseases. The frequencies of ApoE alleles were determined in 291 patients with OSA and 728 controls. The distribution of ApoE alleles and genotypes showed no difference between OSA and controls.