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Polydactyly and fetal hydantoin syndrome: an additional component of the syndrome?
Author(s) -
Yalçinkaya Cengiz,
Tüysüz Beyhan,
Somay Göksel,
Cenani Asim
Publication year - 1997
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/j.1399-0004.1997.tb02485.x
Subject(s) - polydactyly , hydantoin , medicine , craniofacial , hypoplasia , dysostosis , phenytoin , pediatrics , epilepsy , anatomy , congenital disease , biology , biochemistry , psychiatry
We report a 3‐year‐old girl with fetal hydantoin syndrome (FHS) whose mother had received phenytoin 600 mg/day throughout gestation. She had growth retardation, mental deficiency, craniofacial dysmorphism and iris colomobata specific to FHS. However, the patient did not have the distal phalangeal hypoplasia which is associated with FHS; instead, she had Polydactyly of the right foot. This seems to be the first FHS case in the literature with Polydactyly.