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Deletion polymorphism in the angiotensin‐converting enzyme gene is not associated with hypertension in a Gulf Arab population
Author(s) -
Frossard P. M.,
Obineche E. N.,
Elshahat Y. I.,
Lestringant G. G.
Publication year - 1997
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/j.1399-0004.1997.tb02455.x
Subject(s) - abu dhabi , allele , genetics , gene , angiotensin converting enzyme , blood pressure , polymorphism (computer science) , population , biology , allele frequency , renin–angiotensin system , angiotensin ii , medicine , endocrinology , pathology , environmental health , metropolitan area
We have studied an insertion/deletion dimorphism in the human angiotensin‐converting enzyme gene amongst UAE nationals from the Abu Dhabi Emirate. Our findings show lack of association between the I/D allele marker system and clinical diagnosis of essential hypertension, suggesting that variations of the angiotensin‐converting enzyme gene do not play a major role in the determination of elevated blood pressure in this Arab population. This agrees with results reported on other ethnic groups.