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No effect on blood pressure level or variability of polymorphisms in DNA at the locus for atrial natriuretic factor (ANF)
Author(s) -
Berge K. E.,
Berg K.
Publication year - 1994
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/j.1399-0004.1994.tb04412.x
Subject(s) - xhoi , restriction enzyme , locus (genetics) , restriction fragment length polymorphism , blood pressure , genetics , medicine , biology , gene , restriction fragment , endocrinology , genotype , ecori
We have examined healthy Norwegians with respect to two restriction fragment length polymorphisms at the locus for atrial natriuretic factor, detectable with the restriction enzymes XhoI and BglI, respectively. No association with systolic or diastolic blood pressure level or variability was found. Thus, the normal genes detected by examination of these restriction fragment length polymorphisms have neither “level gene” nor “variability gene” effects on normal blood pressure.