Premium
Case reports of malformations associated with maternal diabetes: history and critique
Author(s) -
Kalter Harold
Publication year - 1993
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/j.1399-0004.1993.tb04443.x
Subject(s) - holoprosencephaly , medicine , congenital malformations , dysplasia , family history , diabetes mellitus , congenital disease , pregnancy , pediatrics , fetus , pathology , endocrinology , surgery , genetics , biology
Several malformations and malformation complexes have been alleged to be associated with maternal type 1 diabetes mellitus: in particular, sacral dysplasia, caudal regression/sirenomelia, femoral dysplasia, and holoprosencephaly. For some of the malformations the claim rests on case material, and for others on theoretical considerations. The history and evolution of these ideas are presented.