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Routine applications of DNA fingerprinting with the oligonucleotide probe (CAC) 5 /(GTG) 5
Author(s) -
Neitzel H.,
Digweed M.,
Nürnberg P.,
Pöpperl A.,
Schmidt C. A.,
Tinschert S.,
Sperling K.
Publication year - 1991
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/j.1399-0004.1991.tb02994.x
Subject(s) - oligonucleotide , dna profiling , computational biology , dna , zygosity , bone marrow transplantation , computer science , biology , bone marrow , genetics , immunology
The use of DNA fingerprinting with synthetic oligonucleotides is illustrated for practical applications familiar in clinical diagnostics: pre‐ and postnatal zygosity determination and the monitoring of bone marrow transplantation. A simple method for non‐radioactive detection is described which may be interesting for many diagnostic laboratories.