Premium
Batten disease (Spielmeyer‐Sjogren disease) and haptoglobins (HP): indication of linkage and assignment to chr. 16
Author(s) -
Eiberg H.,
Gardiner R. M.,
Mohr J.
Publication year - 1989
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/j.1399-0004.1989.tb03193.x
Subject(s) - haptoglobin , batten disease , disease , lod score , locus (genetics) , medicine , genetics , biology , gene , gene mapping , chromosome
In a material of 26 Caucasian families, 23 with at least 2 children affected with Batten disease, we found a lod score of 3.00 at theta=0.00 in males and theta=0.26 in females with haptoglobin (HP), and assign the locus for Batten disease to 16q22.