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Trisomy 5 mosaicism in amniotic fluid with normal outcome
Author(s) -
Casamassima Anthony C.,
Wilmot Patrick L.,
Mahoney Maurice J.,
Scott Robin V.,
Shapiro Lawrence R.
Publication year - 1989
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/j.1399-0004.1989.tb02944.x
Subject(s) - amniocentesis , trisomy , amniotic fluid , fetus , aneuploidy , prenatal diagnosis , chorionic villus sampling , medicine , obstetrics , andrology , biology , pregnancy , genetics , chromosome , gene
A case of prenatally diagnosed true mosaicism for trisomy 5 with a clinically normal outcome is presented. Trisomy 5 was detected in 23% of cells obtained by amniocentesis, but it was not detected from cells obtained by fetal blood sampling. While in this case the finding at amniocentesis did not reflect the status of the fetus, care must be exercised in reaching this conclusion in all cases.