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Fertility and X‐chromosome rearrangements: isodicentric X‐chromosome formation in the mother and Xp deletion in her daughter
Author(s) -
Fryns J. P.,
Kleczkowska A.,
Debucquoy P.,
Berghe H.
Publication year - 1988
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/j.1399-0004.1988.tb02885.x
Subject(s) - daughter , karyotype , x chromosome , fertility , genetics , biology , chromosome , population , medicine , gene , evolutionary biology , environmental health
In the present paper we report the first example of fertility in a female with isodicentric X‐formation and karyotype 45,X/46,X,del(X)(pter → p21.3)/46,X,idic(X)(qter →p21.3→p21.3 → qter). Her daughter was phenotypically almost normal and presented a 46,X,del(X)(pter → p21.3) karyotype in all examined cells.