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Three‐generation transmission of Hirschsprung's disease
Author(s) -
Lipson A. H.,
Harvey J.
Publication year - 1987
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/j.1399-0004.1987.tb03350.x
Subject(s) - hirschsprung's disease , medicine , disease , heritability , transmission (telecommunications) , pediatrics , genetics , biology , telecommunications , computer science
A three‐generation family with non‐syndromic biopsy‐proven Hirschsprung's disease involving both short and long segments of the large bowel is reported. Although this is the first three‐generation family reported, it is expected that with the improved diagnosis and treatment that has occurred over the last 30 years further such families will be described, and that the heritability of this condition will be further clarified.