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Dyslexia and chromosome 15 heteromorphism: negative lod score in a Danish material
Author(s) -
Bisgaard M. L.,
Eiberg H.,
Møller N.,
Niebuhr E.,
Mohr J.
Publication year - 1987
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/j.1399-0004.1987.tb03337.x
Subject(s) - danish , dyslexia , genetics , linkage (software) , lod score , backcrossing , biology , genetic linkage , psychology , chromosome , linguistics , gene mapping , reading (process) , gene , philosophy
From a large Danish material of random families we selected families with dyslexia as reported by the families themselves and as recorded by a dyslexia institute. Among five “backcross families” studied for chromosome 15 polymorphisms we found only negative lod scores, and at thêta = 0.10 a negative score of ‐3.42; i.e., in our material we did not find any confirmation of the indication of linkage between dyslexia and a chromosome 15 polymorphism found in part of their material by Smith et al. (1983, 1986).